Innovative Features
The MODERN VECTOR was designed with you in mind.
Each feature was painstakingly engineered and tested to ensure
- your work
- your life
- your success
IS THE NUMBER ONE PRIORITY.
"Look under the hood" to see what you are getting with the MODERN VECTOR.
Hover over for more information
Compact Size
There is a general rule of 10-12Kb maximum for high copy number vectors.
More room for what you want.
At roughly 3.5Kb, these vectors only slightly larger than pUC19, so there is plenty of space available for:
multiple ORFs,
homology arms,
viral LTRs
(to name a few).
Antibiotic Selection
All vectors need selection markers to be propagated in bacteria and it is helpful to have them to select for stable clones in eukaryotes.
1 is all you need
Through a novel promoter active in both prokaryotic and eukaryotic hosts and careful selection of antibiotics, these vectors reduce unwanted sequence that could be added in genomic editing.
Modular Design
Want to change anything? Now you easily can.
Simple Exchanges
Every feature is easily swapped for another.
Want a different main promoter?
Fancy a novel poly-adenylation sequence?
What to put something into the intron?
Now you can readily do that.
Limits are for legacy vectors.
Homology Arm Regions
Homology sequence on either side of the coding region is critical for targeting with genomic editing.
Easy 'cut and ligate' simplicity
The regions for homology arms are carefully positioned, flanked by rare 8 base restriction sites. This allows for easy insertion/revision of the homology arm sequences
and
prevents insertion of the bacterial origin of replication during genomic editing.
RNA Stability
For optimal protein expression, RNA transcript stability is crucial.
Custom Intron
Most vectors use cDNAs for the open reading frame(s) so they lose RNA splicing, which is an important RNA stabilizing mechanism.
By optimally positioning an artificial intron with consensus splice sites, there is enhanced RNA stability resulting in increased protein expression.
Protein Expression
You want to express your protein in a variety of hosts.
One Vector - Many Options
Optimal positioning of both the eukaryotic and powerful T7 promoter permits protein production in a wide variety of settings
prokaryotic, eukaryotic,
and cell free too.
Why have separate vectors for each host, when
one can do it all?
And Many More
All the little things to make your molecular biology life easier.
Rich MCS, High Copy Number, the List Goes On and On.
It is the little things that you count on.
With a rich multiple cloning site, it is easy to move from your current vector to a MODERN VECTOR.
High copy number origin of replication makes it easy to purify large amounts of DNA.
Small size means you aren't as constrained by limitations.
Make the switch today and enjoy what a MODERN VECTOR can do!